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Genome-Environment Interactions in Inflammatory Skin Disease / 2018-02-28

2016 fondos y socioesInflammatory skin diseases affect a significant percentage of our global population. Atopic Dermatitis (AD) affects approximately 10% of children and 3% of adults worldwide. Psoriasis (Pso) affects approximately 2% of our population. These diseases remain poorly understood with limited understanding of their mechanism, endotypes, ontology and co-morbidities, affecting the quality of effective treatments. While there may be aspects of these diseases that overlap, others show little or no similarities e.g. their associated co-morbidities are generally quite distinct with Pso being linked with arthritis, psychiatric disorders, metabolic syndrome and cardiovascular sequelae while AD is associated with rhinitis, asthma, food allergy as well as cardiovascular complications. As a result, there is an immediate need for sophisticated, in-depth investigations of these diseases that address transformative topics. These studies include, but are not limited to, the impact of environmental factors.

European Commission

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